conclusions the best balance between detection rate of prostate cancer and infectious complications of biopsies achieved in twelve-core biopsy protocol. twelve-core biopsy enhances the rate of prostate cancer detection with minimum adverse effects. patients and materials transrectal ultrasonography (trus) guided biopsy was performed in 180 patients suspicious for prostate cancer due to either a...

long-term intravenous immunoglobulin (ivig) infusion is an effective treatment for children with humoral immunodeficiencies, already be complicated by systemic ad¬verse effects. in order to determine the adverse effects of intravenous immunoglobulin inpatients with antibody deficiency, 45 immunodeficientpatients receiving intravenous immunoglobulin were studied during a 36-month period at child...

case presentation we present a case of a grade iii coronary perforation in which the double guiding catheter technique helped us to deliver the graft stent. conclusions the double-guiding technique is useful in emergency situations to increase the safety and efficacy of sealing a coronary perforation. introduction coronary vessel perforation is one of the most feared complications of coronary a...

liver injury occurs with many drugs; therefore, a thorough work up is important for establishing the diagnosis. we report a case of trifluoperazine-induced cholestatic jaundice. a 44-year old male with schizoaffective disorder developed an increase in liver enzymes and jaundice after starting treatment with trifluoperazine. workup for other potential etiologies was negative.

Noise pollution is one of the prominent environmental problems affecting human health especially in developing countries. The impacts of noise on health should not be underestimated. Exposure to acoustical stimuli impairs not only the function of auditory system but also that of many other systems of human body. Previous investigations revealed that noise exposure could result in sleep disturba...

purpose: to investigate tear function in acne vulgaris patients who were treated with isotretinoin (accutane). methods: in this prospective clinical study, patients who were scheduled for isotretinoin (accutane) therapy for two months underwent complete eye examination.the best corrected visual acuity measurement, careful slit lamp examination of anterior segment, evaluation of break-up-time an...

hepatic toxicity is the most serious adverse effect of anti tuberculosis drugs. this study was performed to evaluate efficacy of silymarin as a hepatoprotective herbal agent. in a randomized double blind clinical trial 70 new cases of pulmonary tuberculosis were divided into two groups. the intervention group was assigned to receive silymarin and the control group received placebo. tuberculosis...